Intracellular Signal Transduction: The Jak-Stat Pathway Softcover Repri Edition Contributor(s): Wilks, Andrew F. (Author), Harpur, Ailsa G. (Author) |
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ISBN: 3662220520 ISBN-13: 9783662220528 Publisher: Springer
Binding Type: Paperback Published: November 2013 Click for more in this series: Molecular Biology Intelligence Unit |
Additional Information |
BISAC Categories: - Medical | Oncology - General - Science | Life Sciences - Biology - Science | Life Sciences - Biochemistry |
Dewey: 574.87 |
Series: Molecular Biology Intelligence Unit |
Physical Information: 0.46" H x 7" W x 10" L (0.86 lbs) 209 pages |
Features: Illustrated |
Descriptions, Reviews, Etc. |
Publisher Description: This book is the first one written about the JAK/STAT pathway. The JAK (Janus Kinase) Protein tyrosine kinases are novel phosphotransferases absolutely required for cellular signalling downstream of non-catalytic cytokine receptors (amongst others). These molecules are components in pathways utilising the STAT (Signal Transducers and Activators of Transcription) transcription factors. The basic components of the JAK/STAT pathway are covered in detail, and the centre piece of the book is a guided tour of the pathway itself. An interesting addition to the book is the chapter on the use of Drosophila melanogaster as a genetic system to probe the pathway at the whole organism level. The book is targeted to researchers who have an interest in intracellular signalling. |
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