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Intracellular Signal Transduction: The Jak-Stat Pathway Softcover Repri Edition
Contributor(s): Wilks, Andrew F. (Author), Harpur, Ailsa G. (Author)

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 ISBN: 3662220520     ISBN-13: 9783662220528
Publisher: Springer
OUR PRICE: $104.49  

Binding Type: Paperback
Published: November 2013
Qty:

Click for more in this series: Molecular Biology Intelligence Unit
Additional Information
BISAC Categories:
- Medical | Oncology - General
- Science | Life Sciences - Biology
- Science | Life Sciences - Biochemistry
Dewey: 574.87
Series: Molecular Biology Intelligence Unit
Physical Information: 0.46" H x 7" W x 10" L (0.86 lbs) 209 pages
Features: Illustrated
 
Descriptions, Reviews, Etc.
Publisher Description:
This book is the first one written about the JAK/STAT pathway. The JAK (Janus Kinase) Protein tyrosine kinases are novel phosphotransferases absolutely required for cellular signalling downstream of non-catalytic cytokine receptors (amongst others). These molecules are components in pathways utilising the STAT (Signal Transducers and Activators of Transcription) transcription factors. The basic components of the JAK/STAT pathway are covered in detail, and the centre piece of the book is a guided tour of the pathway itself. An interesting addition to the book is the chapter on the use of Drosophila melanogaster as a genetic system to probe the pathway at the whole organism level. The book is targeted to researchers who have an interest in intracellular signalling.
 
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